Functional magnetic resonance imaging (fMRI) has come under skepticism from researchers questioning the validity of fMRI findings. The amygdala’s anatomical position makes robust fMRI mapping particularly difficult. Responses in the amygdala during emotional tasks was therefore particularly questioned.
We repeated runs of an emotional task during 7T fMRI and varied task instructions and technical factors.
Resting‐state functional magnetic resonance imaging (rs‐fMRI) offers the possibility to assess brain function during rest. This absence of explicit stimuli in fMRI makes analyses more susceptible to noise than task‐based fMRI.
Data preprocessing is a critical procedure to minimise artefacts related to motion and physiology.
A paper recently published in Human Brain Mapping evaluates the effects of different preprocessing strategies on the amplitude of low‐frequency fluctuations (ALFFs) and fractional ALFF (fALFF). We give important recommendations and identified preprocessing strategies that have a negative impact.